Mentor: Munir Tanas, MD

Awarded PhD in Cancer Biology in 2022

Thesis: 

TAZ and YAP dysregulation in sarcomas

Award:

NCI Diversity Supplement, R01 CA237031 (Tanas) "Epigenetic Modulation of the TAZ-CAMTA1 Transcriptional Program by the ADA2A-Containing Histone Acetyltransferase Complex"

Publications:

1. Garcia K, Gingras AC, Harvey KF, Tanas MR. TAZ/YAP fusion proteins: mechanistic insights and therapeutic opportunities. Trends Cancer. Dec 2022;8(12):1033-1045. 

2. Merritt N, Garcia K, Rajendran D, et al. TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. eLife. Apr 29 2021

3. Rytlewski JD, Scalora N, Garcia K, et al. Photodynamic Therapy Using Hippo Pathway Inhibitor Verteporfin: A Potential Dual Mechanistic Approach in Treatment of Soft Tissue Sarcomas. Cancers. Feb 8 2021;13(4)

PubMed