Mentor: Bing Li, PhD

Comprehensive Exam:

Elucidating the Transcriptional Target and Molecular Function of Epidermal-Fatty Acid Binding Protein (FABP5) to Potentiate the Pro-Ferroptotic Effect of Omega-3 Fatty Acid (n-3 FA) in Triple Negative Breast Cancer

Presentations:

2025 3rd Annual Metabolic Dysregulation and Cancer Risk Program (MeDOC) Consortium Meeting. "Olive Oil High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer via Oleic Acid-FABP5-Mediated Oncogenic Pathway." Oral presentation

2025 Holden Comprehensive Cancer Center (HCCC) Cancer Retreat 2025 – "Olive Oil High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer via Oleic Acid-FABP5-Mediated Oncogenic Pathway." Poster presentation

2024 American Association for Cancer Research (AACR) Annual Meeting.  "Omega-3 fatty acid-induced ferroptosis in 4T1 breast cancer through CD36/FABP5 axis."  Poster presentation
 

Awards:

2025 Travel Award. 3rd Annual MeDOC Consortium Meeting 2025 – Boston, Massachusetts
 

Publications:

1. Jiang X, Xiong Y, Yu J, Avellino A, Liu S, Han X, et al. Expression profiles of FABP4 and FABP5 in breast cancer: clinical implications and perspectives. Discover Oncology 16.1 (2025): 357.
2. Yu J, Hao J, Yorek MS, Han X, Avellino A, Jiang X, et al. Determination of the FABP5 expression profile in skin lesions of an IMQ-induced psoriasis mouse model using flow cytometry. STAR Protoc. 2024;5(2):103018.
3. Yorek M, Jiang X, Liu S, Hao J, Yu J, Avellino A, et al. FABP4-mediated lipid accumulation and lipolysis in tumor associated macrophages promote breast cancer metastasis. bioRxiv. 2024. PMC11244950